| Person | Type | Job | Role(s) |
|---|---|---|---|
 John Hankey | Crew | Directing | Director, Writer |
Aubrey Rike | Cast | Self - Ambulance Attendant, Parkland Hospital | |
 Dwight D. Eisenhower | Cast | Actor | Self (archive footage) |
 George H. W. Bush | Cast | Actor | Self (archive footage) |
 John Connally | Cast | Actor | Self - Governor of Texas (archive footage) |
 John F. Kennedy | Cast | Actor | Self (archive footage) |
 Walter Cronkite | Cast | Actor | Self - Anchor, CBS News (voice) (archive audio) |
John Hankey | Cast | Narrator (voice) | |
 Peter Jennings | Cast | Actor | Self - ABC News Reporter |
G. Robert Blakey | Cast | Actor | Self - Chief Counsel for the House Assassinations Committee |
 William Colby | Cast | Self - CIA Director (voice) (archive audio) | |
 George P. Bush | Cast | Actor | Self - Co-director of Union Banking Co. (archive footage) |
 Allen Dulles | Cast | Actor | Self - CIA Director (archive footage) |
 Jack Ruby | Cast | Actor | Self - Former Associate of Richard Nixon (archive footage) |
Andrey Bill | Cast | Actor | Self - Parkland Hospital Nurse (archive footage) |
 Cyril H. Wecht | Cast | Actor | Self - MD, JD, President of Academy of Forensic Sciences |
Aubrey Reich | Cast | Self - Mortuary Technician (archive footage) | |
Charles J. Carrico | Cast | Self - Medical Doctor (archive footage) | |
Mark Weiss | Cast | Self - Acoustics Expert | |
Guy Bannister | Cast | Self - FBI Chicago Chief (archive footage) | |
Ramon Rodriguez | Cast | Self - CIA Covert Operations (archive footage) | |
Richard Bissell | Cast | Self - CIA Director of Operations (archive footage) | |
Eric Hamburg | Cast | Self - Author (archive footage) | |
Waggoner Carr | Cast | Self - Texas, Attorney General (archive footage) | |
Marion Jenkins | Cast | Self - Medical Doctor | |
 Richard M. Bissell Jr. | Cast | Actor | Self - CIA Deputy Director for Plans (archive footage) |
Richard Dulany | Cast | Self - Medical Doctor | |
Charles Cabell | Cast | Self - General, CIA Deputy Director (archive footage) | |
Robert McClelland | Cast | Self - Medical Doctor | |
| Person | Type | Job | Role(s) |
