| Person | Type | Job | Role(s) |
|---|---|---|---|
 Daniel Mandell | Crew | Editing | Editor |
 Frank Maher | Crew | Crew | Sound Recordist |
 Herman J. Mankiewicz | Crew | Writing | Screenplay |
Howard Bristol | Crew | Art | Set Decoration |
 Irving Berlin | Crew | Sound | Songs |
 Jo Swerling | Crew | Writing | Screenplay |
 John Daheim | Crew | Crew | Stunts |
John Sherwood | Crew | Directing | Assistant Director |
 Leigh Harline | Crew | Sound | Original Music Composer |
 Mel Berns | Crew | Costume & Make-Up | Makeup Artist |
Norbert A. Myles | Crew | Costume & Make-Up | Makeup Artist |
Paul Gallico | Crew | Writing | Original Story |
Perry Ferguson | Crew | Art | Art Direction |
René Hubert | Crew | Costume & Make-Up | Costume Design |
 Rudolph Maté | Crew | Camera | Director of Photography |
 Sam Wood | Crew | Directing | Director |
 Samuel Goldwyn | Crew | Production | Producer |
 William Cameron Menzies | Crew | Art | Production Design |
Albert Simpson | Crew | Visual Effects | Matte Painter |
Fletcher Henderson | Crew | Sound | Music Arranger |
 Addison Richards | Cast | Actor | Coach |
 Anita Sharp-Bolster | Cast | Actress | Sasha's Mother (uncredited) |
 Anthony Walters | Cast | Actor | Merril (uncredited) |
Art Rowlands | Cast | Actor | Telephone Man (uncredited) |
 Babe Ruth | Cast | Actor | Babe Ruth |
Becky Bohanon | Cast | Little Girl (uncredited) | |
 Ben Taggart | Cast | Actor | Conductor (uncredited) |
 Betty Brewer | Cast | Little Girl (uncredited) | |
Bill Stern | Cast | Bill Stern | |
Brick Sullivan | Cast | Actor | Policeman (uncredited) |
 Burr Caruth | Cast | Actor | Village Storekeeper (uncredited) |
 C. Montague Shaw | Cast | Actor | Mr. Worthington (uncredited) |
 Charles Cane | Cast | Actor | Plumber (uncredited) |
Charles Flynn | Cast | Actor | Fraternity Boy (uncredited) |
 Charles Irwin | Cast | Actor | Carnival Batting Game Operator (uncredited) |
Charles Williams | Cast | Actor | Little Strength Machine Contestant (uncredited) |
 Clancy Cooper | Cast | Actor | Motorcycle Cop #1 (uncredited) |
 Colin Kenny | Cast | Actor | Yankee Player on Train (uncredited) |
 Cyril Ring | Cast | Actor | Photographer (uncredited) |
 Dan Duryea | Cast | Actor | Hank Hanneman |
 Dane Clark | Cast | Actor | Fraternity Boy (uncredited) |
Dave Manley | Cast | Mayor Fiorello LaGuardia (uncredited) | |
 Don Brodie | Cast | Actor | Girl Show Barker (uncredited) |
Donald Kerr | Cast | Actor | Photographer (uncredited) |
 Dorothy Vaughan | Cast | Actress | Eleanor's Landlady (uncredited) |
 Dorothy Vernon | Cast | Actress | Family Friend (uncredited) |
 Douglas Croft | Cast | Actor | Lou Gehrig as a Boy |
 Earle Hodgins | Cast | Actor | Bottle Game Operator (uncredited) |
Ed Agresti | Cast | Barber (uncredited) | |
 Eddie Hall | Cast | Actor | Reporter in Hospital Room (uncredited) |
 Eddy Chandler | Cast | Actor | Motorcycle Cop #2 (uncredited) |
 Edgar Barrier | Cast | Actor | Hospital Doctor |
 Edward Fielding | Cast | Actor | Clinic Doctor |
 Edward Peil Sr. | Cast | Actor | Policeman (uncredited) |
 Edwin August | Cast | Actor | Restaurant Patron (uncredited) |
 Elsa Janssen | Cast | Actress | Christina 'Mom' Gehrig |
 Emory Parnell | Cast | Actor | Chicago Policeman O'Doul (uncredited) |
 Ernie Adams | Cast | Actor | Miller Huggins |
Ernie Alexander | Cast | Actor | Bellhop with Flowers (uncredited) |
Eva Dennison | Cast | Mrs. Worthington (uncredited) | |
 Fay Holderness | Cast | Actress | Spectator (uncredited) |
Francis Sayles | Cast | Actor | Cab Driver (uncredited) |
Francisco Marán | Cast | Rathskeller Headwaiter (uncredited) | |
 Frank Faylen | Cast | Actor | Yankee Third Base Coach (uncredited) |
 Garry Owen | Cast | Actor | Scorecard Vendor (uncredited) |
 Gary Cooper | Cast | Actor | Henry Louis 'Lou' Gehrig |
Gene Collins | Cast | Actor | Billy (Age 8) |
 George Guhl | Cast | Actor | Second Paper Hanger (uncredited) |
 George Lessey | Cast | Actor | Mayor of New Rochelle |
George McDonald | Cast | Actor | Wally Pipp (uncredited) |
 George Offerman, Jr. | Cast | Actor | Freshman (uncredited) |
Gohr Van Vleck | Cast | Furniture Mover (uncredited) | |
 Guy Wilkerson | Cast | Actor | Sportsman at Ballgame (uncredited) |
Hal Cooke | Cast | Man in Cab (uncredited) | |
 Hardie Albright | Cast | Actor | Van Tuyl |
 Harry Harvey | Cast | Actor | Joe McCarthy |
 Harry Hayden | Cast | Actor | Department Store Manager (uncredited) |
 Heinie Conklin | Cast | Actor | Wallpaper Hanger (uncredited) |
 Henry Roquemore | Cast | Actor | Disappointed Fan #2 (uncredited) |
 Hooper Atchley | Cast | Actor | Lathered Man in Barber Shop (uncredited) |
Irving Mitchell | Cast | Headwaiter (uncredited) | |
 Jack Carr | Cast | Actor | Plumber (uncredited) |
Jack Chapin | Cast | Photographer (uncredited) | |
Jack Irwin | Cast | Photographer in Hospital (uncredited) | |
Jack Shea | Cast | Actor | Hammond (uncredited) |
James McNamara | Cast | Actor | Rathskeller Manager (uncredited) |
 James Westerfield | Cast | Actor | Spectator (uncredited) |
 Janet Chapman | Cast | Tessie (uncredited) | |
John C. McCallum | Cast | Minor Role (uncredited) | |
John Daheim | Cast | Actor | Reporter in Hospital (uncredited) |
John Hiestand | Cast | Actor | Announcer (uncredited) |
 John Ince | Cast | Actor | Man in Box Seat (uncredited) |
 John Kellogg | Cast | Actor | Fraternity Boy (uncredited) |
 Wilmuth Merkyl | Cast | Actor | Spectator (uncredited) |
 John Sheehan | Cast | Actor | First Paper Hanger (uncredited) |
 Lane Chandler | Cast | Actor | Mark - Player in Locker Room (uncredited) |
Larry Lawson | Cast | Barker (uncredited) | |
 Lester Dorr | Cast | Actor | Disappointed Fan #1 (uncredited) |
 Ludwig Stössel | Cast | Actor | Henry 'Pop' Gehrig |
 Lynton Brent | Cast | Actor | Photographer in Hospital (uncredited) |
 Malcolm Waite | Cast | Actor | Big Strength Machine Contestant (uncredited) |
 Mary Gordon | Cast | Actress | Maid (uncredited) |
 Matt McHugh | Cast | Actor | Strength Machine Operator (uncredited) |
Max Willenz | Cast | Actor | Mr. Colletti (uncredited) |
Mike Donovan | Cast | ||
 Mitchell Ingraham | Cast | Actor | Barber (uncredited) |
 Oscar 'Dutch' Hendrian | Cast | Actor | Furniture Mover (uncredited) |
 Pat Flaherty | Cast | Actor | Yankee Ballplayer (uncredited) |
Pat Moriarity | Cast | Actor | Policeman in 1915 (uncredited) |
Patsy O'Byrne | Cast | Actress | Scrubwoman (uncredited) |
Payne B. Johnson | Cast | Boy in Ball Park (uncredited) | |
Peter Du Rey | Cast | Photographer in Hospital (uncredited) | |
 Pierre Watkin | Cast | Actor | Mr. Twitchell |
Ralph McCullough | Cast | Actor | Reporter in Hospital (uncredited) |
 Ray Noble | Cast | Actor | Orchestra Leader (uncredited) |
 Rex Lease | Cast | Actor | Spectator (uncredited) |
Richard Kipling | Cast | Broker (uncredited) | |
Robert Winkler | Cast | Actor | Murphy (uncredited) |
 Rosina Galli | Cast | Actress | Mrs. Fabrini (uncredited) |
Roy Brent | Cast | Actor | Yankee Ballplayer (uncredited) |
 Sarah Padden | Cast | Actress | Mrs. Roberts (uncredited) |
Sheldon Jett | Cast | Actor | Sportsman at Ballgame (uncredited) |
 Spencer Charters | Cast | Actor | Mr. Larsen (uncredited) |
 Teresa Wright | Cast | Actress | Eleanor Twitchell |
 Theodore Lorch | Cast | Actor | Neighbor Leaning Through Window (uncredited) |
 Tom Neal | Cast | Actor | Fraternity Boy (uncredited) |
Tom Quinn | Cast | Actor | Reporter in Hospital (uncredited) |
 Vaughan Glaser | Cast | Actor | Doctor in Gehrig Home (uncredited) |
 Veloz | Cast | Actor | Specialty Dancer (as Veloz and Yolanda) |
 Vinton Hayworth | Cast | Actor | Fraternity Boy (uncredited) |
 Virginia Gilmore | Cast | Actress | Myra Tinsley |
 Walter Brennan | Cast | Actor | Sam Blake |
 Walter Fenner | Cast | Actor | Dentist (uncredited) |
 Walter Tetley | Cast | Actor | Cake Delivery Boy (uncredited) |
 Wilbur Mack | Cast | Actor | Man Outside Yankee Stadium (uncredited) |
 William Roy | Cast | Actor | Joe Fabrini (uncredited) |
 Yolanda | Cast | Actress | Specialty Dancer (as Veloz and Yolanda) |
 Jack Stewart | Cast | Actor | Ed Barrow (uncredited) |
 David Holt | Cast | Actor | Billy (Age 17) |
Maurice Marks | Cast | Actor | Player (uncredited) |
 Howard M. Mitchell | Cast | Actor | Sportsman at Ballgame (uncredited) |
 Herschel Graham | Cast | Actor | Spectator (uncredited) |
Bill Chaney | Cast | Newsboy (uncredited) | |
Pat Lane | Cast | Wheel of Chance Barker (uncredited) | |
 Bill Dickey | Cast | Bill Dickey | |
Bob Meusel | Cast | Robert W. Meusel (as Robert W. Meusel) | |
Mark Koenig | Cast | Mark Koenig | |
Lorna Dunn | Cast | Clinic Nurse (uncredited) | |
| Person | Type | Job | Role(s) |
