| Person | Type | Job | Role(s) |
|---|---|---|---|
 Albie Hecht | Crew | Production | Executive Producer |
 Arlene Klasky | Crew | Production | Producer |
David N. Weiss | Crew | Writing | Writer |
 Eryk Casemiro | Crew | Production | Co-Producer |
 Gábor Csupó | Crew | Production | Producer |
 Igor Kovalyov | Crew | Directing | Director |
J. David Stem | Crew | Writing | Writer |
Jamshied Sharifi | Crew | Crew | Additional Music |
 Julia Pistor | Crew | Production | Co-Producer |
Karyn Rachtman | Crew | Sound | Music Supervisor |
Marco Cinello | Crew | Directing | Layout |
 Mark Mothersbaugh | Crew | Sound | Original Music Composer |
Michael Leung | Crew | Crew | Technical Supervisor |
Norton Virgien | Crew | Directing | Director |
Sharon Ross | Crew | Art | Art Department Manager |
 Sherry Lansing | Crew | Production | Executive In Charge Of Production |
Beth S. Morris | Crew | Crew | Technical Supervisor |
Jim Ovelmen | Crew | Visual Effects | Animation |
John Bryant | Crew | Editing | Editor |
Dima Malantichev | Crew | Art | Art Direction |
Hal Waite | Crew | Production | Co-Producer |
Debby Beece | Crew | Production | Executive Producer |
 Steve Small | Crew | Art | Art Designer |
 Abraham Benrubi | Cast | Actor | Serge (voice) |
 Andrea Martin | Cast | Actress | Aunt Miriam (voice) |
 Beck | Cast | Actor | Newborn Baby (singing voice) |
 Busta Rhymes | Cast | Actor | Reptar Wagon (voice) |
 Charlie Adler | Cast | Actor | United Express Driver (voice) |
 Cheryl Chase | Cast | Actress | Angelica Pickles (voice) |
 Christine Cavanaugh | Cast | Actress | Chuckie Finster (voice) |
 Cree Summer | Cast | Actress | Susie Carmichael (voice) |
 David Spade | Cast | Actor | Ranger Frank (voice) |
Dawn Robinson | Cast | Newborn Baby (singing voice) | |
 Edie McClurg | Cast | Actress | Nurse (voice) |
 Elizabeth Daily | Cast | Actress | Tommy Pickles (voice) |
 Frank Welker | Cast | Actor | Spike / Monkeys / Scar Snout (voice) (uncredited) |
 Fred Schneider | Cast | Actor | Newborn Baby (singing voice) |
 Gordon Gano | Cast | Actor | Newborn Baby (singing voice) |
 Gregg Berger | Cast | Actor | TV Announcer (voice) |
 Hattie Winston | Cast | Actress | Lucy Carmichael (voice) |
 Iggy Pop | Cast | Actor | Newborn Baby (singing voice) |
 Jack Riley | Cast | Actor | Stuart 'Stu' Pickles (voice) |
 Jakob Dylan | Cast | Actor | Newborn Baby (singing voice) |
 Joe Alaskey | Cast | Actor | Grandpa Lou Pickles (voice) |
 Kath Soucie | Cast | Actress | Phil / Lil / Betty DeVille (voices) |
 Laurie Anderson | Cast | Actress | Newborn Baby (singing voice) |
 Lenny Kravitz | Cast | Actor | Newborn Baby (singing voice) |
 Lisa Loeb | Cast | Actress | Newborn Baby (singing voice) |
 Lou Rawls | Cast | Actor | Newborn Baby (singing voice) |
 Margaret Cho | Cast | Actress | Lt. Klavin (voice) |
 Mary Gross | Cast | Actress | Female Guest (voice) |
 Melanie Chartoff | Cast | Actress | Didi Pickles / Minka Kropotkin (voice) |
 Michael Bell | Cast | Actor | Charles 'Chaz' Finster Sr. / Grandpa Boris Kropotkin / Drew Pickles (voice) |
 Patti Smith | Cast | Actress | Newborn Baby (singing voice) |
 Phil Proctor | Cast | Actor | Howard DeVille / Igor (voice) |
 Roger Clinton, Jr. | Cast | Actor | Air Crewman (voice) |
Steve Zirnkilton | Cast | Actor | Reporter (voice) |
 Tara Strong | Cast | Actress | Dilan "Dil" Pickles (voice) |
 Tim Curry | Cast | Actor | Rex Pester (voice) |
 Tony Jay | Cast | Actor | Dr. Lipschitz (voice) |
 Tress MacNeille | Cast | Actress | Charlotte Pickles (voice) |
 Whoopi Goldberg | Cast | Actress | Ranger Margaret (voice) |
Louis Fresse | Cast | Newborn Baby (singing voice) | |
 Kate Pierson | Cast | Actress | Newborn Baby (singing voice) |
 Cindy Wilson | Cast | Actress | Newborn Baby (singing voice) |
Malik Isaac Taylor | Cast | Newborn Baby (singing voice) | |
| Person | Type | Job | Role(s) |
