| Person | Type | Job | Role(s) | Episodes |
|---|---|---|---|---|
 Samantha Bee | Crew | Writing | Writer, Creator | 1 |
 Andre Allen | Crew | Directing | Director | 1 |
 Andrew Rannells | Cast | Actor | Self | 1 |
 Andy Cohen | Cast | Actor | Self | 1 |
 Bellamy Young | Cast | Actress | Self | 1 |
 Bradley Whitford | Cast | Actor | Self | 1 |
 Busy Philipps | Cast | Actress | Self | 1 |
 Caterina Scorsone | Cast | Actress | Self | 1 |
 Catherine O'Hara | Cast | Actress | Self | 1 |
 David Koechner | Cast | Actor | Self | 1 |
 Donald Faison | Cast | Actor | Self | 1 |
 Erin Foley | Cast | Actress | Self | 1 |
 Grace Lynn Kung | Cast | Actress | Self | 1 |
 Harvey Fierstein | Cast | Actor | Self | 1 |
 Jack Black | Cast | Actor | Self | 1 |
 Jane Fonda | Cast | Actress | Self | 1 |
 Jane Lynch | Cast | Actress | Self | 1 |
 Jewel | Cast | Actress | Self | 1 |
 Jimmy Smits | Cast | Actor | Dr. Fauci | 1 |
 Juliana Hatfield | Cast | Actress | Self | 1 |
 Kyle Gass | Cast | Actor | Self | 1 |
 Kyra Sedgwick | Cast | Actress | Self | 1 |
 Lars Ulrich | Cast | Actor | Self | 1 |
 Ludacris | Cast | Actor | Self | 1 |
 Margaret Cho | Cast | Actress | Self | 1 |
 Meredith Salenger | Cast | Actress | Self | 1 |
 Michael Imperioli | Cast | Actor | Self | 1 |
 Michael Lewis | Cast | Actor | Self | 1 |
 Patton Oswalt | Cast | Actor | Self | 1 |
 Regina King | Cast | Actress | Self | 1 |
 Robert De Niro | Cast | Actor | Self | 1 |
 Sarah Silverman | Cast | Actress | Self | 1 |
 Shepard Smith | Cast | Actor | Self | 1 |
 Sigourney Weaver | Cast | Actress | Sigourney Weaver | 1 |
 Steve Buscemi | Cast | Actor | Self | 1 |
 Tony Hale | Cast | Actor | Self | 1 |
 Will Arnett | Cast | Actor | Self | 1 |
 AJ Michalka | Cast | Actress | Self - Musical Guest | 1 |
 Allana Harkin | Cast | Actress | Self | 18 |
 Aly Michalka | Cast | Actress | Self - Musical Guest | 1 |
 Brian Bell | Cast | Actor | Self | 1 |
 Elizabeth Warren | Cast | Actress | Self | 1 |
 Josh Groban | Cast | Actor | Self | 1 |
 June Diane Raphael | Cast | Actress | Self | 1 |
 Peaches | Cast | Actress | Self - Musical Guest | 1 |
Samantha Bee | Cast | Actress | Self - Host | 218 |
 Sara Quin | Cast | Actress | Self | 1 |
 Tegan Quin | Cast | Actress | Self | 1 |
 Tim Gunn | Cast | Actor | Self | 2 |
 Tiya Sircar | Cast | Actress | Self | 1 |
 Amanda Palmer | Cast | Actress | Self - Musical Guest | 1 |
 Joshua Henry | Cast | Actor | Self - Musical Guest | 1 |
 Lauren Ash | Cast | Actress | Self | 1 |
 Marque Richardson | Cast | Actor | Self | 1 |
 William Jackson Harper | Cast | Actor | Self | 1 |
 James Monroe Iglehart | Cast | Actor | Self | 1 |
 Mamrie Hart | Cast | Actress | Self | 1 |
 Nicole Byer | Cast | Actress | Self | 1 |
 Snooki | Cast | Actress | Self | 1 |
 Rebecca Black | Cast | Actress | Self | 1 |
 Alex Newell | Cast | Actor | Self - Musical Guest | 1 |
 Alexandra Grey | Cast | Actress | Self | 1 |
 Alexis Krauss | Cast | Actress | Self | 1 |
 Grace Helbig | Cast | Actress | Self | 1 |
 Ilana Glazer | Cast | Actress | Self | 1 |
 W. Kamau Bell | Cast | Actor | Self | 1 |
 Nyle DiMarco | Cast | Actor | Self | 1 |
 Cynthia Erivo | Cast | Actress | Self | 1 |
Lucia McBath | Cast | Self | 1 | |
 Millicent Simmonds | Cast | Actress | Self | 1 |
 River Butcher | Cast | Self | 1 | |
 Fancy Hagood | Cast | Actor | Self - Musical Guest | 1 |
 Vivian Howard | Cast | Actress | Self | 1 |
 Trixie Mattel | Cast | Actor | Self | 1 |
 Katya Zamolodchikova | Cast | Actor | Self | 1 |
 Aparna Nancherla | Cast | Actress | Self | 1 |
 Marguerite Stimpson | Cast | Actress | Sketch Voter | 1 |
 Richard Marx | Cast | Actor | Self | 1 |
 Amy Hoggart | Cast | Actress | Self | 14 |
 Lawrence Wilkerson | Cast | Actor | Self | 1 |
 Pramila Jayapal | Cast | Actress | Self | 1 |
 Cori Bush | Cast | Actress | Self | 1 |
 April Ryan | Cast | Actress | Self | 1 |
 Karamo Brown | Cast | Actor | Self | 1 |
 Tan France | Cast | Self | 1 | |
 Masha Gessen | Cast | Self | 4 | |
Irene Tu | Cast | Self | 1 | |
 Kirsten Gillibrand | Cast | Actress | Self (archive footage) | 1 |
 Kamala Harris | Cast | Actress | Self | 1 |
 Amy Klobuchar | Cast | Actress | Self | 1 |
 Katie Porter | Cast | Actress | Self | 1 |
 Amber Ruffin | Cast | Self | 1 | |
 Patrick Harvie | Cast | Actor | Self | 1 |
 Rachel Pegram | Cast | Self | 1 | |
 mxmtoon | Cast | Actress | Self | 1 |
 Mike Rubens | Cast | Actor | Self | 15 |
 Michele Mitchell | Cast | Actress | Self | 1 |
 Naomi Ekperigin | Cast | Actress | Self | 1 |
 Amelia Meath | Cast | Actress | Self - Musical Guest | 1 |
 MILCK | Cast | Actress | Self - Musical Guest | 1 |
 Ayanna Pressley | Cast | Actress | Self | 1 |
 Emma Pasarow | Cast | Actress | Self | 1 |
 Ilhan Omar | Cast | Actress | Self | 1 |
 Talesha Wilson | Cast | Actress | Self | 1 |
 Feminista Jones | Cast | Actress | Self | 1 |
 Dale Ho | Cast | Actor | Self | 1 |
 Mike Brown | Cast | Actor | Self | 15 |
 Jamaal Bowman | Cast | Actor | Self | 1 |
 Jon Ossoff | Cast | Actor | Self | 1 |
 Samm Henshaw | Cast | Actor | Self - Musical Guest | 1 |
 Cliff Albright | Cast | Actor | Self | 1 |
 LaTosha Brown | Cast | Actress | Self | 1 |
 David Luban | Cast | Actor | Self | 1 |
 Mondaire Jones | Cast | Actor | Self | 1 |
 Eleanor Holmes Norton | Cast | Actress | Self | 1 |
 Marjorie Taylor Greene | Cast | Actress | Self (archive footage) | 1 |
 Grace Kuhlenschmidt | Cast | Actress | Self | 1 |
Shannon Watts | Cast | Self | 1 | |
Gabby Giffords | Cast | Self | 1 | |
 Shungudzo | Cast | Actress | Self - Musical Guest | 1 |
 VINCINT | Cast | Actor | Self - Musical Guest | 1 |
 Charity Dean | Cast | Actress | Self | 1 |
 Sydnee Washington | Cast | Sydnee Washington | 1 | |
 Derek Miller | Cast | Self | 1 | |
Lori Zaspel | Cast | Self | 1 | |
Jamie Eaddy | Cast | Self | 1 | |
Ryan Burge | Cast | Actor | Self | 1 |
 Alexander Vindman | Cast | Self | 1 | |
 Laura Edelson | Cast | Actress | Self | 1 |
 Jay Van Bavel | Cast | Actor | Self | 1 |
 Renée DiResta | Cast | Actress | Self | 1 |
 Ariana and the Rose | Cast | Actress | Self - Musical Guest | 1 |
 Nicole Perlroth | Cast | Actress | Self | 1 |
 Upsahl | Cast | Actress | Self - Musical Guest | 1 |
 Alessandra Biaggi | Cast | Actress | Self | 1 |
 Susanne Goetz | Cast | Actress | Self | 1 |
 Jen Gunter | Cast | Actress | Self | 1 |
| Person | Type | Job | Role(s) | Episodes |
