Overacted. Overly dramatic. Obnoxious laughtrack. No funny jokes, they fall flat all the time. Often because of lame stereotype jokes no one laughs about in reality anymore.
Is it by accident that the female, lesbian main character Lizzy is wearing similar stuff that Ellen DeGeneres wears? No? I didn't think so. There's more Ellen than Lizzy in this show. Not that this is bad on its own.

I like the premise. It's controversial and a newer version of "The Odd Couple" concept that generally could work today, in opposite of the "reboot" with Matthew Perry. But not how this is worked out here.
Given the premise I find it subtly offensive how the male character plays the dumbass here. The premise doesn't need it and by doing so it decreases the value of this show and its ability to give a social comment.
Cut back on at least half of the awful jokes and establish the underlying, actually believable concept and make fun of its obstacles, especially those given from the society around the characters. You could debunk all the prejudices easily. That would make the show good.
And while you're at it, give some brain to the only male main character, would you? Thanks.