| Person | Type | Job | Role(s) |
|---|---|---|---|
 Cameron Crowe | Crew | Crew | Creative Consultant |
 Gary Goetzman | Crew | Production | Executive Co-Producer |
 Jann Wenner | Crew | Production | Executive Producer |
 Joel Gallen | Crew | Directing | Director, Executive Co-Producer |
 Robbie Robertson | Crew | Crew | Creative Consultant |
 Tom Hanks | Crew | Production | Executive Co-Producer |
 Joel Peresman | Crew | Production | Executive Co-Producer |
Rob Light | Crew | Crew | Creative Consultant |
 Adam Clayton | Cast | Actor | Self |
 Annie Lennox | Cast | Actress | Self |
 Aretha Franklin | Cast | Actress | Self |
 Art Garfunkel | Cast | Actor | Self |
 B.B. King | Cast | Actor | Self |
 Billy Joel | Cast | Actor | Self |
 Bonnie Raitt | Cast | Actress | Self |
 Bono | Cast | Actor | Self |
 Brian Jones | Cast | Actor | Self (archive footage) |
 Bruce Springsteen | Cast | Actor | Self |
 Buddy Guy | Cast | Actor | Self |
 Clarence Clemons | Cast | Actor | Self |
 Darlene Love | Cast | Actress | Self |
 David Crosby | Cast | Actor | Self |
 Dion DiMucci | Cast | Actor | Self |
 Eric Clapton | Cast | Actor | Self (archive footage) |
 Fergie | Cast | Actress | Self |
 Garry Tallent | Cast | Actor | Self |
 Graham Nash | Cast | Actor | Self |
Howlin' Wolf | Cast | Actor | Self (archive footage) |
 James Taylor | Cast | Actor | Self |
 Jeff Beck | Cast | Actor | Self |
 Jerry Lee Lewis | Cast | Actor | Self |
 Jimi Hendrix | Cast | Actor | Self (archive footage) |
 John Fogerty | Cast | Actor | Self |
 Larry Mullen Jr. | Cast | Actor | Self |
 Lenny Bruce | Cast | Actor | Self (archive footage) |
 Lou Reed | Cast | Actor | Self |
 Max Weinberg | Cast | Actor | Self |
 Mick Jagger | Cast | Actor | Self |
 Nils Lofgren | Cast | Actor | Self |
 Ozzy Osbourne | Cast | Actor | Self |
Patti Scialfa | Cast | Self | |
 Patti Smith | Cast | Actress | Self |
 Paul Simon | Cast | Actor | Self |
 Ray Davies | Cast | Actor | Self |
Roy Bittan | Cast | Actor | Self |
Sam Moore | Cast | Actor | Self |
 Smokey Robinson | Cast | Actor | Self |
 Stephen Stills | Cast | Actor | Self |
 Steven Van Zandt | Cast | Actor | Self |
 Stevie Wonder | Cast | Actor | Self |
 Sting | Cast | Actor | Self |
 The Edge | Cast | Actor | Self |
Tom Hanks | Cast | Actor | Host |
 Tal Wilkenfeld | Cast | Actress | Self |
 John Lee Hooker | Cast | Actor | Self (archive footage) |
| Person | Type | Job | Role(s) |
