| Person | Type | Job | Role(s) | Episodes |
|---|---|---|---|---|
 Andrew Nicholls | Crew | Writing | Writer | 10 |
 Butch Hartman | Crew | Writing | Writer, Director | 2 |
 Charles M. Howell IV | Crew | Writing | Story | 1 |
Darrell Vickers | Crew | Writing | Writer | 10 |
Gene Grillo | Crew | Writing | Writer, Screenplay, Story | 23 |
 Gordon Bressack | Crew | Writing | Story | 1 |
 Guy Moon | Crew | Sound | Original Music Composer | 1 |
Jed Spingarn | Crew | Writing | Writer, Story | 12 |
 John A. Davis | Crew | Production | Producer, Story, Writer, Director, Creator | 76 |
 John P. McCann | Crew | Writing | Writer | 1 |
Keith Alcorn | Crew | Production | Producer, Director | 76 |
 Steve Marmel | Crew | Writing | Writer, Screenplay, Story | 3 |
 Steve Oedekerk | Crew | Production | Producer, Writer, Creator | 76 |
 Steven Banks | Crew | Writing | Teleplay, Writer | 1 |
Tom Sheppard | Crew | Writing | Writer | 2 |
Evan Gore | Crew | Writing | Writer | 2 |
Heather Lombard | Crew | Writing | Writer | 2 |
Mike Gasaway | Crew | Directing | Director | 37 |
Rico Hill | Crew | Writing | Story, Idea | 1 |
Jack C. Thomas | Crew | Writing | Story | 1 |
John Crane | Crew | Writing | Writer | 1 |
Kirby Atkins | Crew | Directing | Director | 4 |
Christopher Painter | Crew | Writing | Writer | 4 |
Charlie Brissette | Crew | Sound | Original Music Composer | 79 |
Darwin C. Vickers | Crew | Writing | Writer | 2 |
Spencer Green | Crew | Writing | Writer | 1 |
Mark Menza | Crew | Sound | Original Music Composer | 1 |
 Alyssa Milano | Cast | Actress | April (voice) | 1 |
 Andrea Martin | Cast | Actress | Ms. Fowl / Lady (voice) | 1 |
 Ben Stein | Cast | Actor | Giggles the Clown (voice) | 1 |
 Bill Farmer | Cast | Actor | Buford / Reporter (voice) | 1 |
 Billy West | Cast | Actor | Sam Melnick / Corky Shimatzu / Blix / British Official (voice) | 1 |
 Candi Milo | Cast | Actress | Nick Dean / Woman #1 (voice) | 1 |
 Carlos Alazraqui | Cast | Actor | Mr. Crocker (voice) | 3 |
 Carolyn Lawrence | Cast | Actress | Cindy Vortex / Yuri (voice) | 1 |
 Charlie Adler | Cast | Actor | Junkman (voice) | 2 |
 Christian Slater | Cast | Actor | Jet Fusion (voice) | 2 |
 Corey Burton | Cast | Actor | Dr. Dark / Pizza Monster (voice) | 1 |
 Crystal Scales | Cast | Actress | Libby Folfax / Libby's Mom / Ike (voice) | 1 |
 Dan Castellaneta | Cast | Actor | Professor Crank (voice) | 1 |
 Daran Norris | Cast | Actor | Nanobot #1 (voice) | 2 |
 Debi Derryberry | Cast | Actress | Nissa (voice) | 2 |
 Dee Bradley Baker | Cast | Actor | Binky (voice) | 1 |
 Edie McClurg | Cast | Actress | Grandma Taters (voice) | 2 |
 Frank Welker | Cast | Actor | Tubbs / Special Vocal Effects (voice) | 1 |
 Gary LeRoi Gray | Cast | Actor | A.J. (voice) | 2 |
 Grey DeLisle | Cast | Actress | Vandana (voice) | 1 |
 James Sie | Cast | Actor | You Yee / Elderly Monk / Ninja (voice) | 1 |
 Jason Marsden | Cast | Actor | Chester (voice) | 2 |
 Jay Leno | Cast | Actor | Nega-Chin (voice) | 1 |
 Jeff Bennett | Cast | Actor | Dr. Moist (voice) | 1 |
 Jeff Garlin | Cast | Actor | Villain (voice) | 1 |
 Jeffrey Garcia | Cast | Actor | Army Guard (voice) | 1 |
 Jess Harnell | Cast | Actor | Singing Meldar (voice) | 1 |
 Jim Belushi | Cast | Actor | Coach Gruber (voice) | 3 |
 Jim Cummings | Cast | Actor | Gorlock #1 / Mayor / Dad Gorlock / Gorlocks / Brain #2 (voice) | 1 |
 Jim Meskimen | Cast | Actor | Quentin Smithee (voice) | 1 |
 Joe Lala | Cast | Actor | Mr. Estevez (voice) | 4 |
 John Kassir | Cast | Actor | Seymour / Student #3 (voice) | 1 |
 Kath Soucie | Cast | Actress | Betty Quinlan (voice) | 5 |
 Kevin Michael Richardson | Cast | Actor | Morgan Freeman / Anti-Fairy Walla (voice) | 1 |
Kim Saxon | Cast | Goddard (voice) | 1 | |
 Mark DeCarlo | Cast | Actor | Hugh Neutron / Eddie / Stavros (voice) | 1 |
 Maurice LaMarche | Cast | Actor | Zix / Tee / Reporter (voice) | 1 |
 Megan Cavanagh | Cast | Actress | Judy Neutron / Mrs. Moran (voice) | 1 |
 Mel Brooks | Cast | Actor | Santa Claus (voice) | 1 |
 Michael Clarke Duncan | Cast | Actor | Commander Baker (voice) | 2 |
 Michael Hagiwara | Cast | Actor | Japanese Announcer (voice) | 1 |
 Ming-Na Wen | Cast | Actress | Peggy Tsu (voice) | 1 |
 Neil Ross | Cast | Actor | Announcer (voice) | 1 |
 Paul Greenberg | Cast | Actor | Ooblar / Yokian Waiter / Yokian Waiter (voice) | 1 |
 Peter Frampton | Cast | Actor | Hugh Neutron (singing voice) | 1 |
 Phil LaMarr | Cast | Actor | Bolbi / Pitz / Teenager (voice) | 1 |
 Phyllis Diller | Cast | Actress | Granny Neutron (voice) | 2 |
 Rob Paulsen | Cast | Actor | Big Brother (voice) | 1 |
S. Scott Bullock | Cast | Actor | Goobot (voice) | 1 |
 Tara Strong | Cast | Actress | Timmy Turner (voice) | 3 |
Terry Wood | Cast | Singer (voice) | 1 | |
 Tim Allen | Cast | Actor | Meldar Prime (voice) | 1 |
 Tim Curry | Cast | Actor | Professor Calamitous (voice) | 7 |
 Tom Kane | Cast | Actor | Dean Cain (voice) | 1 |
 Tom Kenny | Cast | Actor | Max / Wilderman / Mr. Moodini (voice) | 1 |
 Tress MacNeille | Cast | Actress | Annabelle / Aunt Kari / Great Aunt Amanda (voice) | 1 |
 Wendie Malick | Cast | Actress | Beautiful Gorgeous (voice) | 3 |
Faith Abrahams | Cast | Francis (voice) | 1 | |
Jeffrey M. Gunn | Cast | Nick Singing (voice) | 1 | |
| Person | Type | Job | Role(s) | Episodes |
