| Person | Type | Job | Role(s) | Episodes |
|---|---|---|---|---|
 Charles S. Dutton | Crew | Directing | Director | 6 |
 David Mills | Crew | Production | Executive Producer, Writer | 6 |
 David Simon | Crew | Production | Executive Producer, Book, Writer, Creator | 6 |
 Ed Burns | Crew | Writing | Book | 6 |
 Jaki Brown | Crew | Production | Casting | 6 |
 Robert F. Colesberry | Crew | Production | Executive Producer | 6 |
Nina K. Noble | Crew | Production | Producer | 6 |
Antonia Ellis | Crew | Production | Co-Producer | 6 |
 Clarke Peters | Cast | Actor | Fat Curt | 6 |
Clayton LeBouef | Cast | Actor | 3 | |
 Corey Parker Robinson | Cast | Actor | R.C. | 6 |
 Cyrus Farmer | Cast | Actor | 4 | |
 Delaney Williams | Cast | Actor | 2 | |
 Don Wallace | Cast | Actor | 1 | |
 Donnell Rawlings | Cast | Actor | 3 | |
 Glenn Plummer | Cast | Actor | George 'Blue' Epps | 6 |
 Khandi Alexander | Cast | Actress | Denise Francine 'Fran' Boyd | 6 |
 Lance Reddick | Cast | Actor | 3 | |
 Maria Broom | Cast | Actress | Bunchie Boyd | 6 |
 Sean Nelson | Cast | Actor | DeAndre McCullough | 6 |
 T.K. Carter | Cast | Actor | Gary McCullough | 6 |
 Tasha Smith | Cast | Actress | Veronica "Ronnie" Boice | 6 |
 Toy Connor | Cast | Actress | Tyreeka Freamon | 6 |
 Tyra Ferrell | Cast | Actress | 4 | |
 Vivian Bang | Cast | Actress | 1 | |
| Person | Type | Job | Role(s) | Episodes |
