| Person | Type | Job | Role(s) | Episodes |
|---|---|---|---|---|
 Francesca Gregorini | Crew | Directing | Director | 2 |
 Katherine Pope | Crew | Production | Executive Producer | 8 |
Liz Heldens | Crew | Production | Executive Producer, Writer | 8 |
 Michael Showalter | Crew | Production | Executive Producer, Director | 8 |
 Amanda Seyfried | Crew | Production | Producer | 8 |
 Elizabeth Meriwether | Crew | Production | Executive Producer, Writer, Creator | 8 |
Jordana Mollick | Crew | Production | Executive Producer | 8 |
 Erica A. Watson | Crew | Directing | Director | 1 |
 Liz Hannah | Crew | Production | Executive Producer, Writer | 8 |
 Matt Lutsky | Crew | Writing | Writer | 1 |
Wei-Ning Yu | Crew | Writing | Writer | 1 |
Hilary Bettis | Crew | Writing | Writer | 1 |
Taylor Dunn | Crew | Production | Executive Producer | 8 |
Rebecca Jarvis | Crew | Production | Executive Producer | 8 |
Victoria Thompson | Crew | Production | Executive Producer | 8 |
Dan LeFranc | Crew | Writing | Writer | 1 |
 Alan Ruck | Cast | Actor | Jay Rosan | 2 |
 Andrew Leeds | Cast | Actor | Roland | 1 |
 Anne Archer | Cast | Actress | Charlotte Shultz | 4 |
 Bill Irwin | Cast | Actor | Channing Robertson | 4 |
 David Burke | Cast | Actor | Lawyer | 1 |
 Ebon Moss-Bachrach | Cast | Actor | John Carreyrou | 3 |
 Elizabeth Marvel | Cast | Actress | Noel Holmes | 5 |
 Jim Hanna | Cast | Actor | Steve Burd | 1 |
 Joe Nieves | Cast | Actor | Patrick | 1 |
 Josh Pais | Cast | Actor | Wade Miquelon | 2 |
 Kate Burton | Cast | Actress | Rochelle Gibbons | 4 |
 Kevin Sussman | Cast | Actor | Mark Roessler | 3 |
 Kurtwood Smith | Cast | Actor | David Boies | 3 |
 Laurie Metcalf | Cast | Actress | Phyllis Gardner | 4 |
 LisaGay Hamilton | Cast | Actress | Judith Baker | 3 |
 Mark Weiler | Cast | Actor | Security Guard #4 | 1 |
 Mary Lynn Rajskub | Cast | Actress | Lorraine Fuisz | 4 |
 Michael Ironside | Cast | Actor | Don Lucas | 2 |
 Michel Gill | Cast | Actor | Chris Holmes | 5 |
 Naveen Andrews | Cast | Actor | Sunny Balwani | 8 |
 Peter James Smith | Cast | Actor | Gary Yamamoto | 1 |
 Sam Waterston | Cast | Actor | George Shultz | 5 |
 Stephen Fry | Cast | Actor | Ian Gibbons | 4 |
 William H. Macy | Cast | Actor | Richard Fuisz | 5 |
Amanda Seyfried | Cast | Actress | Elizabeth Holmes | 8 |
 Amir Arison | Cast | Actor | Avie Tevanian | 1 |
 Angel Parker | Cast | Actress | Interviewer | 1 |
 Bashir Salahuddin | Cast | Actor | Brendan Morris | 3 |
 Davey Johnson | Cast | Actor | Paul | 1 |
 Dylan Minnette | Cast | Actor | Tyler Shultz | 4 |
 James Hiroyuki Liao | Cast | Actor | Edmond Ku | 2 |
 Kristin Lindquist | Cast | Actress | Moderator | 2 |
 Michaela Watkins | Cast | Actress | Linda Tanner | 3 |
 Rich Sommer | Cast | Actor | Kevin Hunter | 1 |
 Sean-Michael Boozer | Cast | Actor | Doctor | 1 |
 Utkarsh Ambudkar | Cast | Actor | Rakesh Dewan | 2 |
 Kate Comer | Cast | Miriam | 1 | |
 Nicky Endres | Cast | Ana Arriola | 1 | |
 Damon K. Sperber | Cast | Boies Lawyer | 1 | |
 Garrett Coffey | Cast | Actor | Billy Evans | 1 |
Piper Major | Cast | Actress | Nurse | 1 |
 Shaun Brown | Cast | Actor | Daniel Young | 3 |
Yossie Mulyadi | Cast | Fired Employee | 1 | |
 June Laporte | Cast | Actress | Tess | 1 |
 Cecily Breaux | Cast | Actress | Beijing Roommate #2 | 1 |
 Ricky Titus-Lam | Cast | Actor | First iPhone Customer | 1 |
 Michael Oosterom | Cast | Actor | Man | 1 |
 Aaron Colom | Cast | Actor | Car Dealer | 1 |
 Steve Trzaska | Cast | Actor | Fanboy | 1 |
 Deep Rai | Cast | Actor | Flirty VC | 1 |
 Patrick Luwis | Cast | Actor | Gavin | 1 |
Elaine Rivkin | Cast | Receptionist | 1 | |
 Zhaleh Vossough | Cast | Actress | Junior Exec | 1 |
 Jeff Bee | Cast | Actor | Herschel | 1 |
 Roberts Jekabsons | Cast | Actor | Customs Agent | 1 |
 Paris Peterson | Cast | Tommy | 1 | |
Troy A. Cephers | Cast | Actor | Security Guard #2 | 1 |
 Micaela Wittman | Cast | Actress | Sorority Girl #1 | 1 |
 Megan Ashley Brown | Cast | Actress | Marcy | 1 |
 Mikaya Fisher | Cast | Actress | Young Elizabeth Holmes | 1 |
 Brad Griffith | Cast | Board Member | 2 | |
 Sam Straley | Cast | Actor | Christian Holmes | 2 |
 Jack Buckley | Cast | Actor | Cute Guy | 1 |
Ryan Ashton | Cast | Cycling Onesie VC | 1 | |
 Syra McCarthy | Cast | Cynthia | 1 | |
 Yumarie Morales | Cast | Actress | Sorority Girl #2 | 1 |
 Lana Danielyan | Cast | Actress | Scientist | 1 |
 Miguel Cohen | Cast | Actor | Security Guard #3 | 1 |
 David Danipour | Cast | Actor | Grad Student | 1 |
Eilene Gil | Cast | Female Employee (Theranos) | 1 | |
Sarah Haruko | Cast | Arizona Doctor | 1 | |
Susan Harmon | Cast | Helena | 1 | |
 Gabriel Oliva | Cast | Bored VC | 1 | |
 Jesten Mariconda | Cast | Shane | 1 | |
 Kari Lee Cartwright | Cast | Actress | Paula Ku | 1 |
Elinor Gunn | Cast | Interviewer | 1 | |
Mike Baker | Cast | Oncology Doctor | 1 | |
 Jake Satow | Cast | Actor | Christian Holmes | 1 |
Eli Revivo | Cast | Actor | Uber Driver | 1 |
Brooke Becker | Cast | Last Assistant | 1 | |
 Camryn Mi-young Kim | Cast | Actress | Erika Cheung | 3 |
Asia Rose Gordon | Cast | Beijing Roommate #3 | 1 | |
Jasmine Lu | Cast | Samantha Ku | 2 | |
Robert J. Chu | Cast | Police Officer | 1 | |
Tice Proctor | Cast | Young Christian Holmes | 1 | |
Pierce Nasser | Cast | Actor | Waiter | 1 |
Laura Estelle | Cast | Beijing Roommate #1 | 1 | |
Robert W. Perkins | Cast | Security Guard #1 | 1 | |
Carolyne Chen | Cast | Emma Ku | 1 | |
 Dave Kumar | Cast | Actor | Officiant | 1 |
Elena Rosa | Cast | Actress | April | 1 |
Robert Batiste | Cast | Messenger | 1 | |
Katie Page | Cast | Patient X | 1 | |
| Person | Type | Job | Role(s) | Episodes |
