| Person | Type | Job | Role(s) | Episodes |
|---|---|---|---|---|
 Charles E. Bastien | Crew | Directing | Director | 39 |
 Deborah Forte | Crew | Production | Executive In Charge Of Production | 52 |
George Arthur Bloom | Crew | Writing | Writer | 23 |
Jane Startz | Crew | Production | Executive Producer | 39 |
Jocelyn Stevenson | Crew | Writing | Writer | 27 |
John May | Crew | Writing | Writer | 14 |
Kristin Laskas Martin | Crew | Writing | Writer | 3 |
Libby Hinson | Crew | Writing | Writer | 2 |
 Little Richard | Crew | Sound | Theme Song Performance | 52 |
 Michael Hirsh | Crew | Production | Executive Producer | 52 |
 Noel MacNeal | Crew | Writing | Writer | 2 |
Patrick Loubert | Crew | Production | Executive Producer | 52 |
Ronnie Krauss | Crew | Writing | Writer | 9 |
Suzanne Bolch | Crew | Writing | Writer | 1 |
Vince Commisso | Crew | Production | Producer | 13 |
Joanna Cole | Crew | Creator | Creator | |
Bruce Degen | Crew | Creator | Creator | |
Clive Smith | Crew | Production | Executive Producer | 39 |
Ellen Schecter | Crew | Writing | Writer | 1 |
Kermit Frazier | Crew | Writing | Writer | 1 |
Alison Blank | Crew | Production | Executive Producer | 13 |
Doug Booth | Crew | Writing | Writer | 1 |
 Alex Trebek | Cast | Actor | (voice) | 1 |
 Amos Crawley | Cast | Actor | Arnold (voice) | 13 |
 Bebe Neuwirth | Cast | Actress | (voice) | 1 |
 Carol Channing | Cast | Actress | 1 | |
 Cindy Williams | Cast | Actress | Gerri Poveri (voice) | 1 |
 Dabney Coleman | Cast | Actor | (voice) | 1 |
 Dan Marino | Cast | Actor | (voice) | 1 |
 Dana Elcar | Cast | Actor | (voice) | 1 |
 Danny Tamberelli | Cast | Actor | Arnold (voice) | 39 |
 Dolly Parton | Cast | Actress | (voice) | 1 |
 Dom DeLuise | Cast | Actor | Baker | 1 |
 Eartha Kitt | Cast | Actress | Mrs. Franklin | 1 |
 Ed Begley Jr. | Cast | Actor | (voice) | 1 |
 Ed Asner | Cast | Actor | (voice) | 1 |
 Edward James Olmos | Cast | Actor | (voice) | 1 |
 Elliott Gould | Cast | Actor | (voice) | 1 |
 Erica Luttrell | Cast | Actress | Keesha (voice) | 52 |
 Jessica Walter | Cast | Actress | (voice) | 1 |
 Lily Tomlin | Cast | Actress | Ms. Frizzle (voice) | 52 |
Maia Filar | Cast | Phoebe (voice) | 52 | |
 Malcolm McDowell | Cast | Actor | (voice) | 1 |
 Malcolm-Jamal Warner | Cast | Actor | The Producer | 52 |
 Matt Frewer | Cast | Actor | (voice) | 1 |
 Michael York | Cast | Actor | (voice) | 1 |
 Paul Winfield | Cast | Actor | (voice) | 4 |
 Rita Moreno | Cast | Actress | (voice) | 1 |
 Robby Benson | Cast | Actor | (voice) | 1 |
 Rosalind Chao | Cast | Actress | Mrs. Li (voice) | 2 |
 Sherman Hemsley | Cast | Actor | Mr. Junkett (voice) | 1 |
 Stuart Stone | Cast | Actor | Ralphie (voice) | 52 |
 Swoosie Kurtz | Cast | Actress | (voice) | 1 |
 Tony Randall | Cast | Actor | (voice) | 1 |
 Tyne Daly | Cast | Actress | (voice) | 1 |
 Wynonna Judd | Cast | Actress | Molly Cule (voice) | 1 |
Andre Ottley-Lorant | Cast | Tim (voice) | 39 | |
Lisa Yamanaka | Cast | Actress | Wanda (voice) | 13 |
 Daniel DeSanto | Cast | Actor | Carlos (voice) | 52 |
Tara Meyer | Cast | Dorothy Ann (voice) | 52 | |
| Person | Type | Job | Role(s) | Episodes |
